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1

Pathophysiology and Mechanisms of Nonalcoholic Fatty Liver Disease

Haas, Joel T., Francque, Sven, Staels, Bart

Journal:

Annual Review of Physiology

Year:

2016

Language:

english

File:

PDF, 1.65 MB

english, 2016

2

Geography of Environmental Risks and Human Security

Neve, Bernadette, Bacquer, Olivier, Caron, Sandrine, Huyvaert, Marlène, Leloire, Audrey, Poulain-Godefroy, Odile, Lecoeur, Cécile, Pattou, François, Staels, Bart, Froguel, Philippe

Journal:

Standort - Zeitschrift für angewandte Geographie

Year:

2014

Language:

german

File:

PDF, 794 KB

german, 2014

3

4,4-Dimethyl-1,2,3,4-tetrahydroquinoline-based PPARα/γ agonists. Part. II: Synthesis and pharmacological evaluation of oxime and acidic head group structural variations

Cécile Parmenon, Jérôme Guillard, Daniel-Henri Caignard, Nathalie Hennuyer, Bart Staels, Valérie Audinot-Bouchez, Jean-Albert Boutin, Catherine Dacquet, Alain Ktorza, Marie-Claude Viaud-Massuard

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 477 KB

english, 2009

4

Bile Acid Control of Metabolism and Inflammation in Obesity, Type 2 Diabetes, Dyslipidemia, and Nonalcoholic Fatty Liver Disease

Chávez-Talavera, Oscar, Tailleux, Anne, Lefebvre, Philippe, Staels, Bart

Journal:

Gastroenterology

Year:

2017

Language:

english

File:

PDF, 2.51 MB

english, 2017

5

Transient increase in obese gene expression after food intake or insulin administration

Saladin, RÃ©gis, De Vos, Piet, Guerre-Millot, Michele, Leturque, Armelle, Girard, Jean, Staels, Bart, Auwerx, Johan

Journal:

Year:

1995

File:

PDF, 757 KB

1995

6

Localization of the Human OB Gene (OBS) to Chromosome 7q32 by Fluorescence in Situ Hybridization

Sandrine Geffroy, Piet De Vos, Bart Staels, Bénédicte Duban, Johan Auwerx, Bérengère de Martinville

Journal:

Year:

1995

File:

PDF, 376 KB

1995

7

Vasoactivity, antioxidant and aphrodisiac properties of Caesalpinia benthamiana roots

Alexis Zamblé, Françoise Martin-Nizard, Sevser Sahpaz, Thierry Hennebelle, Bart Staels, Régis Bordet, Patrick Duriez, Claude Brunet, François Bailleul

Journal:

Journal of Ethnopharmacology

Year:

2008

Language:

english

File:

PDF, 247 KB

english, 2008

8

Thiazolidinediones and PPARγ agonists: time for a reassessment

Bertrand Cariou, Bernard Charbonnel, Bart Staels

Journal:

Trends in Endocrinology & Metabolism

Year:

2012

Language:

english

File:

PDF, 1011 KB

english, 2012

9

Peroxisome proliferator-activated receptors: regulation of transcriptional activities and roles in inflammation

Christophe Blanquart, Olivier Barbier, Jean Charles Fruchart, Bart Staels, Corine Glineur

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2003

Language:

english

File:

PDF, 197 KB

english, 2003

10

Macrophage subsets in atherosclerosis

Chinetti-Gbaguidi, Giulia, Colin, Sophie, Staels, Bart

Journal:

Nature Reviews Cardiology (formerly Nature Clinical Practice Cardiovascular Medicine)

Year:

2014

Language:

english

File:

PDF, 926 KB

english, 2014

11

General Molecular Biology and Architecture of Nuclear Receptors

Pawlak, Michal, Lefebvre, Philippe, Staels, Bart

Journal:

Current Topics in Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 534 KB

english, 2012

12

Prothrombotic factors in histologically proven nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

Verrijken, An, Francque, Sven, Mertens, Ilse, Prawitt, Janne, Caron, Sandrine, Hubens, Guy, Van Marck, Eric, Staels, Bart, Michielsen, Peter, Van Gaal, Luc

Journal:

Year:

2014

Language:

english

File:

PDF, 503 KB

english, 2014

13

Leptin induces osteoblast differentiation of human valvular interstitial cells via the Akt and ERK pathways

Rosa, Mickael, Paris, Camille, Sottejeau, Yoann, Corseaux, Delphine, Robin, Emmanuel, Tagzirt, Madjid, Juthier, Francis, Jashari, Ramadan, Rauch, Antoine, Vincentelli, André, Staels, Bart, Van Belle,

Journal:

Acta Diabetologica

Year:

2017

Language:

english

File:

PDF, 2.36 MB

english, 2017

14

Horloges circadiennes et métabolisme : intégration des signaux métaboliques et environnementaux

Duez, Hélène, Sebti, Yasmine, Staels, Bart

Journal:

médecine/sciences

Year:

2013

Language:

french

File:

PDF, 985 KB

french, 2013

15

Pirfenidone Is an Agonistic Ligand for PPARÎ± and Improves NASH by Activation of SIRT1/LKB1/pAMPK

SandovalâRodriguez, Ana, MonroyâRamirez, Hugo Christian, MezaâRios, Alejandra, GarciaâBaÃ±uelos, Jesus, VeraâCruz, Jose, GutiÃ©rrezâCuevas, Jorge, SilvaâGomez, Jorge, Staels, Bart, Domin

Journal:

Hepatology Communications

Year:

2020

Language:

english

File:

PDF, 2.32 MB

english, 2020

16

Schistosoma mansoni schistosomula reduce E-selectin and VCAM-1 expression in TNF-α-stimulated lung microvascular endothelial cells by interfering with the NF-κB pathway

François Trottein, Sophie Nutten, Véronique Angeli, Philippe Delerive, Elisabeth Teissier, André Capron, Bart Staels, Monique Capron

Journal:

European Journal of Immunology

Year:

1999

Language:

english

File:

PDF, 166 KB

english, 1999

17

Peroxisome proliferator-activated receptor γ activators affect the maturation of human monocyte-derived dendritic cells

Philippe Gosset, Anne-Sophie Charbonnier, Philippe Delerive, Josette Fontaine, Bart Staels, Joel Pestel, André-Bernard Tonnel, François Trottein

Journal:

European Journal of Immunology

Year:

2001

Language:

english

File:

PDF, 174 KB

english, 2001

18

Schistosoma mansoni induces the synthesis of IL-6 in pulmonary microvascular endothelial cells: role of IL-6 in the control of lung eosinophilia during infection

Véronique Angeli, Christelle Faveeuw, Philippe Delerive, Josette Fontaine, Yara Barriera, Nathalie Franchimont, Bart Staels, Monique Capron, François Trottein

Journal:

European Journal of Immunology

Year:

2001

Language:

english

File:

PDF, 238 KB

english, 2001

19

[4-(2H-1,2,3-Benzotriazol-2-yl)phenoxy]alkanoic Acids as Agonists of Peroxisome Proliferator-Activated Receptors (PPARs)

Anna Sparatore, Cristina Godio, Elena Perrino, Sergio Romeo, Bart Staels, Jean-Charles Fruchart, Maurizio Crestani

Journal:

Chemistry & Biodiversity

Year:

2006

Language:

english

File:

PDF, 114 KB

english, 2006

20

Characterization of New PPARγ Agonists: Analysis of Telmisartan’s Structural Components

Matthias Goebel, Markus Clemenz, Bart Staels, Thomas Unger, Ulrich Kintscher, Ronald Gust

Journal:

Year:

2009

Language:

english

File:

PDF, 854 KB

english, 2009

21

Characterization of New PPARγ Agonists: Benzimidazole Derivatives – the Importance of Position 2

Matthias Goebel, Bart Staels, Thomas Unger, Ulrich Kintscher, Ronald Gust

Journal:

Year:

2009

Language:

english

File:

PDF, 386 KB

english, 2009

22

The liver X-receptor alpha controls hepatic expression of the human bile acid–glucuronidating UGT1A3 enzyme in human cells and transgenic mice

Mélanie Verreault, Kathy Senekeo-Effenberger, Jocelyn Trottier, Jessica A. Bonzo, Julie Bélanger, Jenny Kaeding, Bart Staels, Patrick Caron, Robert H. Tukey, Olivier Barbier

Journal:

Year:

2006

Language:

english

File:

PDF, 741 KB

english, 2006

23

Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis

Kristiaan Wouters, Patrick J. van Gorp, Veerle Bieghs, Marion J. Gijbels, Hans Duimel, Dieter Lütjohann, Anja Kerksiek, Roger van Kruchten, Nobuyo Maeda, Bart Staels, Marc van Bilsen, Ronit Shiri-Sver

Journal:

Year:

2008

Language:

english

File:

PDF, 3.05 MB

english, 2008

24

Kupffer cells promote hepatic steatosis via interleukin-1β–dependent suppression of peroxisome proliferator-activated receptor α activity

Rinke Stienstra, Fredy Saudale, Caroline Duval, Shohreh Keshtkar, Johanna E. M. Groener, Nico van Rooijen, Bart Staels, Sander Kersten, Michael Müller

Journal:

Year:

2010

Language:

english

File:

PDF, 2.53 MB

english, 2010

25

A central role for cholesterol metabolism and inflammation during the inhibition of non-alcoholic steatohepatitis with a synthetic PPARα agonist

Kristiaan Wouters, Marc van Bilsen, Veerle Bieghs, Patrick J. van Gorp, Dieter Lütjohann, Anja Kerksiek, Bart Staels, Marten H. Hofker, Ronit Shiri-Sverdlov

Journal:

Chemistry and Physics of Lipids

Year:

2008

Language:

english

File:

PDF, 57 KB

english, 2008

26

Studies towards the conception of new selective PPARβ/δ ligands

Carine Ekambomé Basséne, Franck Suzenet, Nathalie Hennuyer, Bart Staels, Daniel-Henri Caignard, Catherine Dacquet, Pierre Renard, Gérald Guillaumet

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 135 KB

english, 2006

27

Design and synthesis of highly potent and selective human peroxisome proliferator-activated receptor α agonists

Yukiyoshi Yamazaki, Kazutoyo Abe, Tsutomu Toma, Masahiro Nishikawa, Hidefumi Ozawa, Ayumu Okuda, Takaaki Araki, Soichi Oda, Keisuke Inoue, Kimiyuki Shibuya, Bart Staels, Jean-Charles Fruchart

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 150 KB

english, 2007

28

4,4-Dimethyl-1,2,3,4-tetrahydroquinoline-based PPARα/γ agonists. Part I: Synthesis and pharmacological evaluation

Cécile Parmenon, Jérôme Guillard, Daniel-Henri Caignard, Nathalie Hennuyer, Bart Staels, Valérie Audinot-Bouchez, Jean-Albert Boutin, Catherine Dacquet, Alain Ktorza, Marie-Claude Viaud-Massuard

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 182 KB

english, 2008

29

Novel non-carboxylic acid retinoids: 1,2,4-Oxadiazol-5-one derivatives

Julie Charton, Rebecca Deprez-Poulain, Nathalie Hennuyer, Anne Tailleux, Bart Staels, Benoit Deprez

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 182 KB

english, 2009

30

Expression and Localization of Peroxisome Proliferator-Activated Receptors and Nuclear Factor kappaB in Normal and Lesional Psoriatic Skin

Westergaard, Majken, Henningsen, Jeanette, Johansen, Claus, Rasmussen, Sofie, Svendsen, Morten Lyhne, Jensen, Uffe Birk, Schroder, Henrik Daa, Staels, Bart, Iversen, Lars, Bolund, Lars, Kragballe, Knu

Journal:

The Journal of Investigative Dermatology

Year:

2003

Language:

english

File:

PDF, 1.95 MB

english, 2003

31

Obesity resistant mechanisms in the Lean polygenic mouse model as indicated by liver transcriptome and expression of selected genes in skeletal muscle

Matjaž Simončič, Tadeja Režen, Peter Juvan, Damjana Rozman, Gregor Fazarinc, Catherine Fievet, Bart Staels, Simon Horvat

Journal:

Year:

2011

Language:

english

File:

PDF, 329 KB

english, 2011

32

Effects of Microdesmis keayana alkaloids on vascular parameters of erectile dysfunction

Alexis Zamblé, Françoise Martin-Nizard, Sevser Sahpaz, Marie-Line Reynaert, Bart Staels, Régis Bordet, Patrick Duriez, Bernard Gressier, François Bailleul

Journal:

Phytotherapy Research

Year:

2009

Language:

english

File:

PDF, 130 KB

english, 2009

33

Antipsychotic drug action on SREBPs-related lipogenesis and cholesterogenesis in primary rat hepatocytes

Emilie Lauressergues, Bart Staels, Karine Valeille, Zouher Majd, Dean W. Hum, Patrick Duriez, Didier Cussac

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2010

Language:

english

File:

PDF, 429 KB

english, 2010

34

Overweight induced by chronic risperidone exposure is correlated with overexpression of the SREBP-1c and FAS genes in mouse liver

Emilie Lauressergues, Françoise Martin, Audrey Helleboid, Emmanuel Bouchaert, Didier Cussac, Régis Bordet, Dean Hum, Gérald Luc, Zouher Majd, Bart Staels, Patrick Duriez

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2011

Language:

english

File:

PDF, 342 KB

english, 2011

35

Is the current therapeutic armamentarium in diabetes enough to control the epidemic and its consequences? What are the current shortcomings?

Dario Giugliano, Eberhard Standl, Tina Vilsbøll, John Betteridge, Riccardo Bonadonna, Ian W. Campbell, Gerit-Holger Schernthaner, Bart Staels, Antonia Trichopoulou, Eduardo Farinaro

Journal:

Acta Diabetologica

Year:

2009

Language:

english

File:

PDF, 226 KB

english, 2009

36

Effects ofPinus pinasterandPinus koraiensisseed oil supplementation on lipoprotein metabolism in the rat

Gaëlle Asset, Bart Staels, Robert L. Wolff, Eric Baugé, Zouher Madj, Jean-Charles Fruchart, Jean Dallongeville

Journal:

Year:

1999

Language:

english

File:

PDF, 480 KB

english, 1999

37

The role of fibric acids in atherosclerosis

Jean-Charles Fruchart, Bart Staels, Patrick Duriez

Journal:

Current Atherosclerosis Reports

Year:

2001

Language:

english

File:

PDF, 464 KB

english, 2001

38

Pleiotropic effects of fibrates

Giulia Chinetti-Gbaguidi, Jean Charles Fruchart, Bart Staels

Journal:

Current Atherosclerosis Reports

Year:

2005

File:

PDF, 513 KB

2005

39

Efficacy of peroxisome proliferator-activated receptor agonists in diabetes and coronary artery disease

Catherine Fiévet, Bart Staels

Journal:

Current Atherosclerosis Reports

Year:

2009

Language:

english

File:

PDF, 257 KB

english, 2009

40

Bile Acid Sequestrants for Lipid and Glucose Control

Bart Staels, Yehuda Handelsman, Vivian Fonseca

Journal:

Current Diabetes Reports

Year:

2010

Language:

english

File:

PDF, 244 KB

english, 2010

41

Bile Acid Metabolism and the Pathogenesis of Type 2 Diabetes

Janne Prawitt, Sandrine Caron, Bart Staels

Journal:

Current Diabetes Reports

Year:

2011

Language:

english

File:

PDF, 274 KB

english, 2011

42

Characterization of new PPARγ agonists: Benzimidazole derivatives—importance of positions 5 and 6, and computational studies on the binding mode

Matthias Goebel, Gerhard Wolber, Patrick Markt, Bart Staels, Thomas Unger, Ulrich Kintscher, Ronald Gust

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.44 MB

english, 2010

43

Colesevelam lowers glucose and lipid levels in type 2 diabetes: the clinical evidence

Vivian A. Fonseca, Yehuda Handelsman, Bart Staels

Journal:

Diabetes, Obesity and Metabolism

Year:

2010

Language:

english

File:

PDF, 586 KB

english, 2010

44

Human retinoic acid receptor-related orphan receptor α1 overexpression protects neurones against oxidative stress-induced apoptosis

Fatiha Boukhtouche, Guilan Vodjdani, Christopher I. Jarvis, Joelle Bakouche, Bart Staels, Jacques Mallet, Jean Mariani, Yolande Lemaigre-Dubreuil, Bernard Brugg

Journal:

Journal of Neurochemistry

Year:

2006

Language:

english

File:

PDF, 438 KB

english, 2006

45

The glucocorticoid receptor is a co-regulator of the orphan nuclear receptor Nurr1

Rodolphe Carpentier, Paola Sacchetti, Pascaline Ségard, Bart Staels, Philippe Lefebvre

Journal:

Journal of Neurochemistry

Year:

2008

Language:

english

File:

PDF, 604 KB

english, 2008

46

Glitazones in the treatment of cardiovascular risk factors

Mohamed Amine Bouhlel, Giulia Chinetti-Gbaguidi, Bart Staels

Journal:

Fundamental & Clinical Pharmacology

Year:

2007

Language:

english

File:

PDF, 79 KB

english, 2007

47

Fenofibrate, a peroxisome proliferator–activated receptor-α agonist, exerts anticonvulsive properties

Natacha Porta, Louis Vallée, Cécile Lecointe, Emmanuel Bouchaert, Bart Staels, Régis Bordet, Stéphane Auvin

Journal:

Year:

2009

Language:

english

File:

PDF, 237 KB

english, 2009

48

Visfatin is induced by peroxisome proliferator-activated receptor gamma in human macrophages

Thérèse Hèrvée Mayi, Christian Duhem, Corinne Copin, Mohamed Amine Bouhlel, Elena Rigamonti, François Pattou, Bart Staels, Giulia Chinetti-Gbaguidi

Journal:

Year:

2010

Language:

english

File:

PDF, 389 KB

english, 2010

49

PPAR Tissue Distribution and Interactions with Other Hormone-Signaling Pathways

THOMAS LEMBERGER, OLIVIER BRAISSANT, CRISTIANA JUGE-AUBRY, HANSJÖRG KELLER, RÉGIS SALADIN, BART STAELS, JOHAN AUWERX, ALBERT G. BURGER, CHRISTOPH A. MEIER, WALTER WAHLI

Journal:

Annals of the New York Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.10 MB

english, 1996

50

PPARs: Transcription Factors Controlling Lipid and Lipoprotein Metabolism

VIRGINIE BOCHER, INÉS PINEDA-TORRA, JEAN-CHARLES FRUCHART, BART STAELS

Journal:

Annals of the New York Academy of Sciences

Year:

2002

Language:

english

File:

PDF, 2.73 MB

english, 2002

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